June 2025
New paper on
bioRxiv: "
Strategies to improve the efficiency of homing gene drives with multiplexed gRNAs."
The Champer Lab welcomes undergraduate researcher Emma Yao.
New paper on
bioRxiv: "
A systematic delineation of 3′UTR regulatory elements and their contextual associations."
New paper on
bioRxiv: "
Investigating multiple types of resistance against a homing gene drive in European populations of Drosophila melanogaster."
May 2025
Congratulations to Xiaozhen Yang for giving a talk at the International Forum for Surveillance and Control of Mosquitoes and Mosquito-borne Diseases.
Talk at the International Forum for Surveillance and Control of Mosquitoes and Mosquito-borne Diseases conference.
Paper published in
Cellular and Molecular Life Sciences: "
β2-tubulin regulates the development and migration of eupyrene sperm in Spodoptera frugiperda."
The Champer Lab welcomes undergraduate researcher Andrea Tan.
April 2025
New paper on
bioRxiv: "
Gene drive dynamics in plants: the role of seedbanks."
Seminar at AgriFutures. Thanks to host Olivia Reynolds.
New paper on
bioRxiv: "
Stronger population suppression by gene drive targeting doublesex from dominant female-sterile resistance alleles."
Paper published in
BMC Biology: "
A self-limiting sterile insect technique alternative for Ceratitis capitata."
March 2025
Seminar at York University. Thanks to hosts Joshua Ang and Luke Alphey.
Seminar at Imperial College London. Thanks to host Angela Meccariello.
Seminar at University of Oxford. Thanks to hosts Ziqian Xu and Michael Bonsall.
New paper on
bioRxiv: "
Aedes aegypti aminopeptidase N3 is a functional binding receptor of Bacillus thuringiensis subsp. israelensis Cry4Ba toxin."
New paper on
bioRxiv: "
A simulation-based deep learning framework for spatially explicit malaria modeling of CRISPR suppression gene drive mosquitoes."
Seminar at Wageningen University and Research. Thanks to hosts Nicky Faber, Bart Pannebakker, Bas Zwaan, and Joost van den Heuvel.
Seminar at the Indian Institute of Science. Thanks to host Saskya Daly Van Nouhuys.
Seminar at National University of Singapore. Thanks to hosts Henry Mok and Cai Yu.
New paper on
bioRxiv: "
Modeling control of invasive fire ants by gene drive."
February 2025
Paper published in
Molecular Biology and Evolution: "
A comparative assessment of self-limiting genetic control strategies for population suppression."
January 2025
Paper published in
Nature Communications: "
Gene drive-based population suppression in the malaria vector Anopheles stephensi."
Seminar at University of Oregon. Thanks to host Peter Ralph.
Seminar at University of Otago. Thanks to host Peter Dearden.
Paper published in
Journal of Pest Science: "
Assessment of drive efficiency and resistance allele formation of a homing gene drive in the mosquito Aedes aegypti."
Seminar at Vietnam Academy of Science and Technology. Thanks to hosts Nguyen Thi Dieu Thuy and Do Tien Phat.
Seminar at Vietnam National University. Thanks to host Tran Duc Long.
Seminar at Hanoi University of Science and Technology. Thanks to hosts Truong Quoc Phong and Nguyen Tien Thanh.
Seminar at Ton Duc Thang University. Thanks to host Nguyen Ngoc Tuan.
Seminar at Nong Lam University. Thanks to host Nguyen Bao Quoc.
Seminar at Nguyen Tat Thanh University. Thanks to host Le Minh Bui.
December 2024
Seminar at the National Institute of Infectious Diseases (Tokyo). Thanks to host Shinji Kasai.
New paper on
bioRxiv: "
Assessing target genes for homing suppression gene drive."
Seminar at High School Affiliated to Renmin University. Thanks to host Feng Li.
November 2024
Seminar at Gannan Normal University. Thanks to host Wei Chen.
Seminar at Korea Science Academy of KAIST. Thanks to host Ki Youb Park.
Seminar at Seoul National University. Thanks to host Youngsung Joo.
Talk at the Zhongshan Academic Festival.
Seminar at Zhejiang University. Thanks to host Jia Huang.
October 2024
The Champer Lab welcomes undergraduate researcher Xiaohan Xie.
Paper published in
Methods in Nature Communications: "
Improving the suppressive power of homing gene drive by co-targeting a distant-site female fertility gene."
The Champer Lab welcomes rotating graduate student Yunchen Xia.
Paper published in
Methods in Ecology and Evolution: "
Resource-explicit interactions in spatial population models."
Seminar at Chongqing Normal University. Thanks to host Zhengbo He.
Congratulations to Jie Du, Xuejiao Xu, and Yiran Liu for giving talks at the Chinese Entomological Society conference in Chongqing.
Talk at the Chinese Entomological Society conference.
Review published in
Annual Review of Entomology: "
Gene drive and symbiont technologies for control of mosquito-borne diseases."
September 2024
New paper on
bioRxiv: "
Assessment of drive efficiency and resistance allele formation of a homing gene drive in the mosquito Aedes aegypti."
New paper on
bioRxiv: "
A comparative assessment of self-limiting genetic control strategies for population suppression."
Paper published in
Molecular Ecology: "
Deployment of tethered gene drive for confined suppression in continuous space requires avoiding drive wave interference."
Paper published in
Nature Communications: "
Population suppression by release of insects carrying a dominant sterile homing gene drive targeting doublesex in Drosophila."
Paper published in
BMC Biology: "
Population suppression with dominant female-lethal alleles is boosted by homing gene drive."
The Champer Lab welcomes undergraduate researcher Siyan Wu.
The Champer Lab welcomes rotating graduate students Xinyi Wang, Ruishan Lyu, Yiming Liu, Jiajun Zhang.
August 2024
Congratulations to Jie Du, Xuejiao Xu, Yiran Liu, Weizhe Chen, Ruobing Feng, Yingke Wu, Xinyue Zhang, Xiaozhen Yang, Yue Han, Jialiang Guo, Jinyu Zhu, Nicky Faber, Jiahe (Carol) Li, Weitang Sun, and Chengwei Shi for giving talks at the International Congress of Entomology meeting in Kyoto.
New paper on
bioRxiv: "
Population dynamics in spatial suppression gene drive models and the effect of resistance, density dependence, and life history."
July 2024
Review published in
Journal of Insect Science: "
Battles between ants (Hymenoptera: Formicidae): a review."
Talk at the Society for Mathematical Biology Meeting.
Congratulations to Yiran Liu, Xinyue Zhang, and Jiahe (Carol) Li for giving talks at the Society for Mathematical Biology Meeting in Seoul.
June 2024
New paper on
bioRxiv: "Deployment of tethered gene drive for confined suppression in continuous space requires avoiding drive wave interference." (final version published in September 2024)
Paper published in
Proceedings B: "
Performance characteristics allow for confinement of a CRISPR toxin-antidote gene drive for population suppression in a reaction-diffusion model."
Paper published in
Nature Plants: "
Overriding Mendelian inheritance in Arabidopsis with a CRISPR toxin-antidote gene drive that impairs pollen germination."
New Presentation Online at HSTalks: "
Different types of gene drives."
The Champer Lab welcomes undergraduate researcher Ziyin Yao.
May 2024
Paper published in
Nature Communications: "
Germline Cas9 promoters with improved performance for homing gene drive."
New paper on
bioRxiv: "
Gene drive-based population suppression in the malaria vector Anopheles stephensi."
April 2024
Paper published in
Journal of Genetics and Genomics: "
A homing rescue gene drive with multiplexed gRNAs reaches high frequency in cage populations but generates functional resistance."
Paper published in
PLoS Genetics: "
A small-molecule approach to restore female sterility phenotype targeted by a homing suppression gene drive in the fruit pest Drosophila suzukii."
Paper published in
International Journal of Biological Macromolecules: "
Involvement of miR-8510a-3p in response to Cry1Ac protoxin by regulating PxABCG3 in Plutella xylostella."
March 2024
Talk at the Malaria Vector Control Technologies Conference.
Talk at the Gene Drive Research Forum Meeting.
The Champer Lab welcomes undergraduate researcher Peixin Wu.
The Champer Lab welcomes high school researcher Xiaokuan Wang.
February 2024
The Champer Lab welcomes lab manager Yang Zhang.
January 2024
New paper on
bioRxiv: "Resource-explicit interactions in spatial population models." (final version published in October 2024)
The Champer Lab welcomes postdoc Christopher Kruger (joint with Bo Zhang's lab).
December 2023
Postdoc Yuan Hu Allegretti has left the lab for an academic editor position. Her main manuscript from the lab is expected later in 2024.
New paper on
bioRxiv: "
Improving the suppressive power of homing gene drive by co-targeting a distant-site female fertility gene." (final version published in October 2024)
New paper on
bioRxiv: "Population suppression with dominant female-lethal alleles is boosted by homing gene drive." (final version published in September 2024)
The Champer Lab welcomes rotating graduate student Nan Chen.
November 2023
New paper on
bioRxiv: "A homing rescue gene drive with multiplexed gRNAs reaches high frequency in cage populations but generates functional resistance." (final version published in April 2024)
Paper published in
Molecular Ecology Resources: "
A framework for identifying fertility gene targets for mammalian pest control."
Congratulations to Yuan Hu Allegretti for giving a talk at the BRIN Mathematics of Malaria Transmission Dynamics in College Park, Maryland.
Talk at the BRIN Mathematics of Malaria Transmission Dynamics conference.
The Champer Lab welcomes rotating graduate student Kunyu Wang.
October 2023
The Champer Lab welcomes rotating graduate student Hongjun Long.
Congratulations to Jie Du for presenting at the China
Drosophila Biology Conference.
Congratulations to Xuejiao Xu, Yuan Hu Allegretti, Shibo Hou, Rachel Zhou, and Mollyann Qi for giving talks at the International Conference on Insect Pest Management in Nanjing.
Talk at the International Conference on Insect Pest Management conference.
New paper on
bioRxiv: "Overriding Mendelian inheritance in
Arabidopsis with a CRISPR toxin-antidote gene drive that impairs pollen germination." (final version published in June 2024)
September 2023
Paper published in
Molecular Ecology: "
Making waves: Comparative analysis of gene drive spread characteristics in a continuous space model."
Seminar at Chinese Academy of Sciences Institute of Genetics and Developmental Biology. Thanks to host Wenfeng Qian.
The Champer Lab welcomes rotating graduate student Yue Han.
August 2023
Congratulations to Weizhe Chen for presenting at the Chinese Entomological Society conference in Kunming.
The Champer Lab welcomes postdoc Jie Yang and visiting graduate student Xiaozhen Yang.
Congratulations to Jie Du, Xuejiao Xu, Yuan Hu Allegretti, Yiran Liu, Jingheng Chen, and Mollyann Qi for giving talks at the International Conference on Insect Science in Baoding.
The Champer Lab welcomes visiting graduate student Mollyann Qi.
July 2023
Congratulations to Jie Du, Xuejiao Xu, Yiran Liu, Weizhe Chen, and Jiahe (Carol) Li for giving talks at the International Congress of Genetics in Melbourne.
New paper on
bioRxiv: "Population suppression by release of insects carrying a dominant sterile homing gene drive targeting
doublesex in
Drosophila." (final version published in September 2024)
New paper on
bioRxiv: "New germline Cas9 promoters show improved performance for homing gene drive." (final version published in May 2024)
June 2023
New paper on
bioRxiv: "A framework for identifying fertility gene targets for mammalian pest control." (final version published in November 2023)
Congratulations to Mingzuyu Pan for completing her undergraduate thesis work and successfully graduating!
May 2023
Paper published in
Ecology Letters: "
Adversarial interspecies relationships facilitate population suppression by gene drive in spatially explicit models."
Seminar at Nanjing Agricultural University. Thanks to host Shunfan Wu.
Jackson is appointed as a visiting professor at Fujian Agriculture and Forestry University.
Seminar at Fujian Agriculture and Forestry University. Thanks to host Minsheng You.
April 2023
Congratulations to Jie Du for giving a talk at the National Symposium on Green Prevention and Control of Crop Diseases and Pests and Biotechnology.
The Champer Lab congratulates Yiran Liu for winning a competitive award to attend the SMBE meiotic drive workship in June.
March 2023
The Champer Lab welcomes volunteer researcher Yuna Cho.
The Champer Lab welcomes rotating graduate student Moming Guo.
The Champer Lab welcomes undergraduate researcher Ziye Wang.
February 2023
Paper published in
ACS Synthetic Biology: "
Simulations reveal high efficiency and confinement of a population suppression CRISPR toxin-antidote gene drive."
Paper published in
Frontiers in Bioengineering and Biotechnology: "
Assessment of distant-site rescue elements for CRISPR toxin-antidote gene drives."
January 2023
The Champer Lab welcomes undergraduate researcher Chengwei Shi.
Paper published in
PLoS Genetics: "
Harnessing Wolbachia cytoplasmic incompatibility alleles for confined gene drive: A modeling study."
New paper on
bioRxiv: "Assessment of distant-site rescue elements for CRISPR toxin-antidote gene drives." (final version published in February 2023)
The Champer Lab welcomes volunteer researcher Shibo Hou.
December 2022
New paper on
bioRxiv: "Performance characteristics allow for confinement of a CRISPR toxin-antidote gene drive designed for population suppression in a reaction-diffusion model." (final version published in June 2024)
The Champer Lab welcomes undergraduate researcher Jialing Fang.
The Champer Lab welcomes rotating graduate student Wenqing Tian.
November 2022
The Champer Lab welcomes rotating graduate students Xuqing Feng and Weiwen Yang.
New paper on
bioRxiv: "Making waves: Comparative analysis of gene drive spread characteristics in a continuous space model." (final version published in September 2023)
New paper on
bioRxiv: "Simulations reveal high efficiency and confinement of a population suppression CRISPR toxin-antidote gene drive." (final version published in February 2023)
October 2022
The Champer Lab welcomes rotating graduate students Biao Zhang and Cao Yu.
Paper published in
eLife (last postdoc paper!): "
Anopheles homing suppression drive candidates exhibit unexpected performance differences in simulations with spatial structure."
Online seminar at France National Research Institute for Agriculture, Food and Environment. Thanks to host Nicolas Rode.
September 2022
Paper published in
eLife: "
Fitness effects of CRISPR endonucleases in Drosophila melanogaster populations."
The Champer Lab welcomes high school researcher Ruizhi (Rachel) Zhou.
The Champer Lab welcomes undergraduate researcher Jinyu Zhu.
The Champer Lab welcomes rotating graduate students Ruobing Feng and Yinke Wu.
August 2022
New paper on
bioRxiv: "Harnessing
Wolbachia cytoplasmic incompatibility alleles for confined gene drive: a modeling study." (final version published in January 2023)
July 2022
The Champer Lab welcomes rotating graduate student Xinyue Zhang.
June 2022
The Champer Lab welcomes undergraduate researchers Weitang Sun and Yuqi Zhang.
Congratulations to Shijie Zhang, WeiJian Teo, Haochen Yang, and Weizhe Chen for completing their undergraduate thesis work and successfully graduating!
May 2022
Paper published in
BMC Biology: "
Experimental demonstration of tethered gene drive systems for confined population modification or suppression."
New paper on
bioRxiv: "Adversarial interspecies relationships facilitate population suppression by gene drive in spatially explicit models." (final version published in May 2023)
April 2022
Paper published in
Proceedings B (first paper of the new lab!): "
Modelling homing suppression gene drive in haplodiploid organisms." Congratulations, Yiran!
Paper published in
G3: "
A homing suppression gene drive with multiplexed gRNAs maintains high drive conversion efficiency and avoids functional resistance alleles."
March 2022
New paper on
bioRxiv: "Finding the strongest gene drive: Simulations reveal unexpected performance differences between
Anopheles homing suppression drive candidates." (final version published in October 2022)
The Champer Lab welcomes undergraduate researcher Mingzuyu Pan.
Review published in
Trends in Genetics: "
Symbionts and gene drive: two strategies to combat vector-borne disease."
February 2022
The Champer Lab welcomes undergraduate researcher Xiaozhen Yang.
December 2021
Paper published in
PLOS Computational Biology: "
Modeling CRISPR gene drives for suppression of invasive rodents."
The Champer Lab welcomes undergraduate researcher Weizhe Chen.
The Champer Lab welcomes volunteer researcher Jingheng Chen.
November 2021
The Champer Lab welcomes volunteer researcher Ziqian Xu.
Review article published in
Journal of Great Lakes Research: "Genetic control of invasive sea lamprey in the Great Lakes."
October 2021
The Champer Lab welcomes undergraduate researcher Jiahe (Carol) Li.
Talk at the Chinese Entomological Society conference.
New paper on
bioRxiv: "Modeling homing suppression gene drive in haplodiploid organisms." (final version published in April 2022)
September 2021
The Champer Lab welcomes rotating graduate student Siyang Zhou.
August 2021
Seminar at the Chinese Academy of Sciences Institute of Zoology. Thanks to hosts Zhen Zou and Guan-Hong Wang.
The Champer Lab welcomes undergraduate researchers Shijie Zhang and WeiJian Teo.
The Champer Lab welcomes volunteer reseacher Weiwei Chen.
The Champer Lab welcomes lab manager Li (Lily) Yang.
July 2021
The Champer Lab welcomes postdoc researcher Xuejiao Xu.
The Champer Lab welcomes research technician Xihua Jia.
June 2021
Talk at the Interdisciplinary Workshop on Synthetic Gene Drives. "Gene drive for population modification or suppression.”
The Champer Lab welcomes undergraduate researcher Yutong Zhu.
May 2021
New paper on
bioRxiv: "Experimental demonstration of tethered gene drive systems for confined population modification or suppression." (final version published in May 2022)
The Champer Lab welcomes research technician Yiran Liu.
New paper on
bioRxiv: "A homing suppression gene drive with multiplexed gRNAs maintains high drive conversion efficiency and avoids functional resistance alleles." (final version published in April 2022)
Jackson has arrived at Peking University. Special thanks to new lab members Jie Du (postdoc), Chenyi Chu (researcher), and Haonan Yang (graduate student) for helping to set things up.
New paper on
bioRxiv: "Fitness effects of CRISPR endonucleases in
Drosophila melanogaster populations" (final version published in September 2022)
Participated in the Target Malaria workshop "Plausible Pathways to Potential Harm"
----Start of the Champer Lab at Peking University on 21 May----
February 2021
Talk at the Canadian Conference for Fisheries Research annual meeting. "Population control of invasive fish using gene drive”
January 2021Paper published in Molecular Ecology: "Suppression gene drive in continuous space can result in unstable persistence of both drive and wild‐type alleles."
December 2020
The Champer Lab welcomes Jie Du, a newly recruited postdoc who will join the lab when it opens in early 2021.
Paper published in
Evolutionary Applications: "Design and analysis of CRISPR‐based underdominance toxin‐antidote gene drives
"
November 2020
New paper on bioRxiv: "Modeling CRISPR gene drives for suppression of invasive rodents
" (final version published in December 2021)
Jackson has accepted a faculty position at the
School of Life Sciences at Peking University and the Peking-Tsinghua Center for Life Sciences.
September 2020
Paper published in PNAS: "A CRISPR homing gene drive
targeting a haplolethal gene removes resistance alleles and successfully spreads through a cage
population"
March 2020
Paper published in BMC Biology: "Performance analysis
of novel toxin-antidote CRISPR gene drive systems"
Press: Cornell researchers find safer approach to gene drives
Press: Improved CRISPR gene drive
solves problems of old tech
Press: TARE May Be the Future of Genome Editing, Improving on CRISPR Gene Drive
Paper published in ACS Synthetic
Biology: "Population dynamics of underdominance
gene drive systems in continuous space"
An NIH/NIAID K22 grant has been funded for Jackson Champer, which will support
his future laboratory.
Paper
published in Science Advances: "Computational and experimental performance of CRISPR homing gene drive strategies with
multiplexed gRNAs"
February
2020
Paper published in Nature Communications: "A toxin-antidote CRISPR gene drive
system for regional population modification"
December 2019
New paper on bioRxiv: "Design and analysis of CRISPR-based underdominance toxin-antidote gene drives" (final version published in December 2020)
November
2019
Congratulations to Emily Yang for presenting a talk at the Entomology Society of America Conference! "A CRISPR homing gene drive targeting a haplolethal gene with rescue averts resistance
"
Talk at the Entomology Society of America Conference. "Experimental
and computational tests of CRISPR toxin-antidote gene drive strategies
”
October 2019
Congratulations to Emily Yang for receiving a Cornell research grant for our
experiments!
September
2019
New paper on bioRxiv
"Suppression gene drive
in continuous space can result in unstable persistence of both drive and wild-type alleles" (final version published in January 2021)
July
2019
Talk at the EMBO Vector conference. "Experimental and computational tests of new gene drive
strategies"
Talk at the
Sea Lamprey International Symposium. “CRISPR gene drive as a tool for control of the sea
lamprey”
June 2019
Seminar at
the University of Melbourne. “Experimental and computational tests of novel CRISPR gene drive
strategies”
Participated in the ILSI workshop "Gene Drive Modeling Conference"
New paper on bioRxiv: "Computational and experimental
performance of CRISPR homing gene drive strategies with multiplexed gRNAs" (final version published in March 2020)
Talk at the Evolution 2019 joint
conference. "Computational and experimental tests of new
CRISPR gene drive strategies"
Congratulations to Isabel Kim for
being selected as a member of the Hunter R. Rawlings III Cornell Presidential Research Scholars
Program!
May
2019
Congratulations to Emily Yang for winning the Cornell Molecular and Cellular
Biology poster competition! "A CRISPR gene drive eliminates resistance with haplolethal target and rescue
allele"
New paper on bioRxiv: "Performance analysis of
novel toxin-antidote CRISPR gene drive systems" (final version published
in March 2020)
New paper on bioRxiv: "A toxin-antidote CRISPR
gene drive system for regional population modification" (final version
published in February 2020)
Participated in the FNIH workshop
"Data Needs and Assay Design for Decision Making on Gene Drive-Modified Mosquitoes"
New paper on bioRxiv: "Resistance is futile: A CRISPR homing gene drive targeting a haplolethal
gene" (final version published in September
2020)
Congratulations to Isabel Kim for presenting a poster at the Great Lakes Evolutionary Genomics
Symposium! "Suppression gene drives in continuous space can demonstrate unstable long-term population
dynamics"
April 2019
Congratulations to Jingxian Liu and Zhaoxin Wen for completing their honors thesis
requirements! These theses were based on their Genetics papers published in January and March of this
year.
Press: eLife
Podcast
March 2019
Paper published in Genetics: "CRISPR gene
drive efficiency and resistance rate is highly heritable with no common genetic loci of large
effect"
Press: Keeping gene drives
in check
January 2019
Paper published in eLife: "Molecular safeguarding of CRISPR gene drive
experiments"
Paper published in Genetics: "Maximum likelihood estimation of fitness
components in experimental evolution"
Press: Scientists demonstrate effective strategies for safeguarding CRISPR gene-drive
experiments
November 2018
Talk at the Entomological Society of America Joint Annual Meeting. "Can CRISPR gene drive succeed in natural
populations?"
October 2018
New paper on bioRxiv: "Population dynamics of underdominance gene
drive systems in continuous space" (final version published in March
2020)
New paper on bioRxiv: "Multiple loci of
small effect confer wide variability in efficiency and resistance rate of CRISPR gene drive" (final version published in March 2019)
September 2018
New paper on bioRxiv:
"Molecular safeguarding of CRISPR gene drive experiments" (final version
published in January 2019)
Congratulations to Jingxian Liu for receiving a Cornell research grant
for our experiments!
August 2018
Congratulations to Zhaoxin Wen for presenting a talk at the Cornell undergraduate
research symposium! "A genome-wide association study to identify genetic factors affecting CRISPR gene
drives"
June
2018
New paper on bioRxiv: "Maximum likelihood estimation of fitness components in
experimental evolution" (final version published in January
2019)
May 2018
Paper published in PNAS:
"Reducing resistance allele
formation in CRISPR gene drive"
Poster presentation at the Genetics
Society of America PEQG Conference. "A genome-wide association study to identify genetic factors affecting
resistance allele formation in CRISPR gene drives”
Press: Researchers Hit Roadblocks
with Gene Drives
April 2018
Grant awarded: NIH F32
"Dynamics of gene drives in natural populations"
Talk at the Genetics
Society of America Drosophila Research Conference. "A genome-wide association study to identify genetic factors affecting
resistance allele formation in CRISPR gene drives”
Congratulations to Jingxian Liu for receiving
the Victoria Finnerty Undergraduate Travel Award and
presenting a talk at the Genetics Society of America Drosophila Research Conference! "Maximum
likelihood estimation of sex-dependent fitness costs of a yellow mutant allele in Drosophila
melanogaster"
November 2017
Congratulations to Chen Liu and Jingxian Liu for presenting a poster at the Ivy
League Undergraduate Research Symposium! "Characterization and Improvement of CRISPR Homing Gene
Drives"
August 2017
Grant awarded: NIH R21 "Improved CRISPR
gene drive systems with reduced resistance allele formation"
Congratulations to Joan Chung and Chen Liu for
presenting a talk at the Cornell undergraduate research symposium! "Applications and development of homing gene
drives"
July 2017
Paper published in PLOS Genetics:
"Novel
CRISPR/Cas9 gene drive constructs reveal insights into mechanisms of resistance allele formation and drive
efficiency in genetically diverse populations"
Talk at the Cold
Spring Harbor CRISPR Conference. "CRISPR gene drives with reduced resistance allele
formation"
Public Outreach: "Ask Me Anything" on Reddit
Press:
Gene Drives Will Need a Tune-Up to Power Past Resistance
Gene drives likely to be
foiled by rapid rise of resistance
Resistance to CRISPR gene drives may arise easily
Genetically Engineering Nature Will Be Way More Complicated Than We Thought
The gene
drive bubble: New realities
June
2017
New paper on bioRxiv: "Reducing resistance allele formation in CRISPR gene drives"
(final version published in May 2018)
April 2017
Poster
presentation at the Genetics Society of America Drosophila Research Conference. "Resistance allele formation and genetic diversity in Drosophila CRISPR/Cas9 gene
drives"
February 2017
New paper on
bioRxiv: "Novel CRISPR/Cas9 gene drive constructs in Drosophila reveal insights into mechanisms of
resistance allele formation and drive efficiency in genetically diverse populations" (final version published in
July 2017)
May 2016
Jackson Champer
joins the Messer and Clark labs at Cornell University as a postdoc