September 2022
Paper published in eLife: "Fitness effects of CRISPR endonucleases in Drosophila melanogaster populations".
The Champer Lab welcomes high school researcher Ruizhi (Rachel) Zhou.
The Champer Lab welcomes undergraduate researchers Zexuan Lu and Jinyue Zhu.
The Champer Lab welcomes rotating graduate students Ruobing Feng and Yinke Wu.
June 2022
The Champer Lab welcomes undergraduate researchers Weitang Sun and Yuqi Zhang.
Congratulations to Shijie Zhang, WeiJian Teo, Haochen Yang, and Weizhe Chen for completing their undergraduate thesis work and successfully graduating!
March 2022
New paper on bioRxiv: "Finding the strongest gene drive: Simulations reveal unexpected performance differences between Anopheles homing suppression drive candidates" (updated version published in October 2022)
The Champer Lab welcomes undergraduate researcher Mingzuyu Pan.
Review published in Trends in Genetics: "Symbionts and gene drive: two strategies to combat vector-borne disease"
February 2022
The Champer Lab welcomes undergraduate researcher Xiaozhen Yang.
October 2021
The Champer Lab welcomes undergraduate researchers Jiahe (Carol) Li and Xinyue Zhang.
Talk at the Chinese Entomological Society conference.
New paper on bioRxiv: "Modeling homing suppression gene drive in haplodiploid organisms" (updated version published in April 2022)
September 2021
The Champer Lab welcomes rotating graduate student Siyang Zhou.
August 2021
Seminar at the Chinese Academy of Sciences Institute of Zoology. Thanks to hosts Zhen Zou and Guan-Hong Wang.
The Champer Lab welcomes undergraduate researchers Shijie Zhang and WeiJian Teo.
The Champer Lab welcomes volunteer reseacher Weiwei Chen.
The Champer Lab welcomes lab manager Li (Lily) Yang.
July 2021
The Champer Lab welcomes postdoc researcher Xuejiao Xu.
The Champer Lab welcomes research technician Xihua Jia.
June 2021
Talk at the Interdisciplinary Workshop on Synthetic Gene Drives. "Gene drive for population modification or suppression”
The Champer Lab welcomes undergraduate researcher Yutong Zhu.
May 2021
New paper on bioRxiv: "Experimental demonstration of tethered gene drive systems for confined population modification or suppression" (updated version published in May 2022)
The Champer Lab welcomes research technician Yiran Liu.
New paper on bioRxiv: "A homing suppression gene drive with multiplexed gRNAs maintains high drive conversion efficiency and avoids functional resistance alleles" (updated version published in April 2022)
Jackson has arrived at Peking University. Special thanks to new lab members Jie Du (postdoc), Chenyi Chu (researcher), and Haonan Yang (graduate student) for helping to set things up.
New paper on bioRxiv: "Fitness effects of CRISPR endonucleases in Drosophila melanogaster populations" (updated version published in September 2022)
Participated in the Target Malaria workshop "Plausible Pathways to Potential Harm"
----Start of the Champer Lab at Peking University on 21 May----
February 2021
Talk at the Canadian Conference for Fisheries Research annual meeting. "Population control of invasive fish using gene drive”
December 2020
The Champer Lab welcomes Jie Du, a newly recruited postdoc who will join the lab when it opens in early 2021.
Paper published in Evolutionary Applications: "Design and analysis of CRISPR‐based underdominance toxin‐antidote gene drives
"
November 2020 New paper on bioRxiv: "Modeling CRISPR gene drives for suppression of invasive rodents" (updated version published in December 2021)
Jackson has accepted a faculty position at the School of Life Sciences at Peking University and the Peking-Tsinghua Center for Life Sciences.
December 2019 New paper on bioRxiv: "Design and analysis of CRISPR-based underdominance toxin-antidote gene drives" (updated version published in December 2020)
November
2019
Congratulations to Emily Yang for presenting a talk at the Entomology Society of AmericaConference! "A CRISPR homing gene drive targeting a haplolethal gene with rescue averts resistance" Talk at the Entomology Society of AmericaConference. "Experimental
and computational tests of CRISPR toxin-antidote gene drive strategies”
October 2019 Congratulations to Emily Yang for receiving a Cornell research grant for our
experiments!
September
2019 New paper on bioRxiv
"Suppression gene drive
in continuous space can result in unstable persistence of both drive and wild-type alleles" (updated version published in January 2021)
July
2019 Talk at the EMBO Vector conference. "Experimental and computational tests of new gene drive
strategies" Talk at the
Sea Lamprey International Symposium. “CRISPR gene drive as a tool for control of the sea
lamprey”
June 2019 Seminar at
the University of Melbourne. “Experimental and computational tests of novel CRISPR gene drive
strategies” Participated in the ILSI workshop "Gene Drive Modeling Conference" New paper on bioRxiv: "Computational and experimental
performance of CRISPR homing gene drive strategies with multiplexed gRNAs" (updated version published in March 2020) Talk at the Evolution 2019 joint
conference. "Computational and experimental tests of new
CRISPR gene drive strategies" Congratulations to Isabel Kim for
being selected as a member of the Hunter R. Rawlings III Cornell Presidential Research Scholars
Program!
May
2019 Congratulations to Emily Yang for winning the Cornell Molecular and Cellular
Biology poster competition! "A CRISPR gene drive eliminates resistance with haplolethal target and rescue
allele" New paper on bioRxiv: "Performance analysis of
novel toxin-antidote CRISPR gene drive systems" (updated version published
in March 2020) New paper on bioRxiv: "A toxin-antidote CRISPR
gene drive system for regional population modification" (updated version
published in February 2020) Participated in the FNIH workshop
"Data Needs and Assay Design for Decision Making on Gene Drive-Modified Mosquitoes" New paper on bioRxiv: "Resistance is futile: A CRISPR homing gene drive targeting a haplolethal
gene" (updated version published in September
2020) Congratulations to Isabel Kim for presenting a poster at the Great Lakes Evolutionary Genomics
Symposium! "Suppression gene drives in continuous space can demonstrate unstable long-term population
dynamics"
April 2019 Congratulations to Jingxian Liu and Zhaoxin Wen for completing their honors thesis
requirements! These theses were based on their Genetics papers published in January and March of this
year. Press: eLife
Podcast
November 2018 Talk at the Entomological Society of America Joint Annual Meeting. "Can CRISPR gene drive succeed in natural
populations?"
October 2018 New paper on bioRxiv: "Population dynamics of underdominance gene
drive systems in continuous space" (updated version published in March
2020) New paper on bioRxiv: "Multiple loci of
small effect confer wide variability in efficiency and resistance rate of CRISPR gene drive" (updated version published in March 2019)
September 2018 New paper on bioRxiv:
"Molecular safeguarding of CRISPR gene drive experiments" (updated version
published in January 2019) Congratulations to Jingxian Liu for receiving a Cornell research grant
for our experiments!
August 2018 Congratulations to Zhaoxin Wen for presenting a talk at the Cornell undergraduate
research symposium! "A genome-wide association study to identify genetic factors affecting CRISPR gene
drives"
June
2018 New paper on bioRxiv: "Maximum likelihood estimation of fitness components in
experimental evolution" (updated version published in January
2019)
April 2018 Grant awarded: NIH F32
"Dynamics of gene drives in natural populations" Talk at the Genetics
Society of America Drosophila ResearchConference. "A genome-wide association study to identify genetic factors affecting
resistance allele formation in CRISPR gene drives” Congratulations to Jingxian Liu for receiving
the Victoria Finnerty Undergraduate Travel Award and
presenting a talk at the Genetics Society of America Drosophila ResearchConference! "Maximum
likelihood estimation of sex-dependent fitness costs of a yellow mutant allele in Drosophila
melanogaster"
November 2017 Congratulations to Chen Liu and Jingxian Liu for presenting a poster at the Ivy
League Undergraduate Research Symposium! "Characterization and Improvement of CRISPR Homing Gene
Drives"
August 2017 Grant awarded: NIH R21 "Improved CRISPR
gene drive systems with reduced resistance allele formation" Congratulations to Joan Chung and Chen Liu for
presenting a talk at the Cornell undergraduate research symposium! "Applications and development of homing gene
drives"
February 2017 New paper on
bioRxiv: "Novel CRISPR/Cas9 gene drive constructs in Drosophila reveal insights into mechanisms of
resistance allele formation and drive efficiency in genetically diverse populations" (updated version published in
July 2017)
May 2016 Jackson Champer
joins the Messer and Clark labs at Cornell University as a postdoc